Investigators from UConn Health Have Reported New Data on Alzheimer Disease (Bace1 Regulates Expression of Clusterin In Astrocytes for Enhancing Clearance of Beta-amyloid Peptides).

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Zdroj: Pain & Central Nervous System Week; 7/3/2023, p649-649, 1p
Abstrakt: Keywords: Farmington; State:Connecticut; United States; North and Central America; Alzheimer Disease; Amyloid; Astrocytes; Clusterin; Glycoproteins; Molecular Chaperones; Neurodegenerative Diseases and Conditions; Neuroglia; Peptide Hormones; Peptide Proteins; Peptides; Peptides and Proteins; Proinsulin; Proteins; Proteomics EN Farmington State:Connecticut United States North and Central America Alzheimer Disease Amyloid Astrocytes Clusterin Glycoproteins Molecular Chaperones Neurodegenerative Diseases and Conditions Neuroglia Peptide Hormones Peptide Proteins Peptides Peptides and Proteins Proinsulin Proteins Proteomics 649 649 1 07/03/23 20230703 NES 230703 2023 JUL 7 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Current study results on Neurodegenerative Diseases and Conditions - Alzheimer Disease have been published. We compared the transcriptomes of astrocyte and reactive astrocyte clusters and identified several differentially expressed genes, which were further validated using Bace1 KO astrocyte cultures. [Extracted from the article]
Databáze: Complementary Index