A New Chloro-Containing γ-Butyrolactone from the Mangrove Endophytic Fungus Neofusicoccum parvum Y2NBKZG1016.

Autor:	Xie, Xiaoting, Xiao, Suping, Liao, Huiyi, Jiang, Qingjian, Chen, Gang, Wen, Lu
Předmět:	ENDOPHYTIC fungi MANGROVE plants NITRIC oxide LIPOPOLYSACCHARIDES METABOLITES
Zdroj:	Chemistry of Natural Compounds; May2023, Vol. 59 Issue 3, p424-427, 4p
Abstrakt:	A new chloro-containing γ-butyrolactone derivative 1, together with eight known metabolites (2–9), were isolated from the mangrove endophytic fungus Neofusicoccum parvum Y2NBKZG1016. Its structure was identified as (4S,5S,6S,7R)-4-(3-chloro-1,2-dihydroxybutyl)-butyrolactone (1) by spectral data and chemical method. The otoprotective effects of all compounds and the ability of 1 to inhibit the release of lipopolysaccharide (LPS)-induced nitric oxide (NO) from RAW264.7 were determined. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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