| Autor: |
Wang, Peile, Xing, Han, Zhang, Xiaojian, Yang, Jing |
| Předmět: |
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| Zdroj: |
Clinical Infectious Diseases; 6/15/2023, Vol. 76 Issue 12, p2209-2210, 2p |
| Abstrakt: |
The article discusses the complex interactions between nirmatrelvir/ritonavir and voriconazole in patients with COVID-19. Both medications have drug-drug interactions and affect drug-metabolizing enzymes. The study observed changes in voriconazole concentrations when coadministered with nirmatrelvir/ritonavir, influenced by CYP2C19 genotypes. Further research is needed for dose adjustment recommendations. Therapeutic drug monitoring of voriconazole is advised during coadministration. |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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