The influence of information processing speed on benefit from learning and memory rehabilitation in TBI: a sub-analysis of the TBI-MEM trial.
| Autor: | Chiaravalloti, Nancy D., Costa, Silvana, Armknecht, Caroline, Costanza, Kristen, Alexander, Aubree, DeLuca, John |
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THOUGHT & thinking
MEMORY STATISTICS COGNITION disorders COGNITIVE processing speed LEARNING PLACEBOS RANDOMIZED controlled trials TREATMENT effectiveness NEUROPSYCHOLOGICAL tests ACADEMIC achievement BLIND experiment DESCRIPTIVE statistics DATA analysis DATA analysis software REHABILITATION for brain injury patients |
| Zdroj: | Brain Injury; 2023, Vol. 37 Issue 8, p689-696, 8p |
| Abstrakt: | This study examined the influence of processing speed (PS) on benefit from treatment with the Kessler Foundation modified Story Memory Technique® (KF-mSMT®), a cognitive rehabilitation intervention shown to improve new learning and memory in traumatic brain injury (TBI). Non-profit research center 62 participants with moderate-to-severe TBI were included, 31 assigned to the treatment group and 31 to the placebo-control group. Double-blind, placebo-controlled, randomized clinical trial. The present study represents a post-hoc analysis to examine the role of PS on treatment efficacy. Baseline and follow-up neuropsychological assessment including the California Verbal Learning Test, Second Edition (CVLT-II), Memory Assessment Scales – Prose Memory (MAS-PM) and the Symbol Digit Modalities Test (SDMT). A treatment effect was not observed on the CVLT-II learning slope in the treatment group relative to the placebo group post-treatment, after co-varying for education, baseline CVLT slope and PS performance. However, performance on a measure of PS, the SDMT, was a significant predictor of post-treatment change following KF-mSMT® treatment. PS was not a significant predictor of benefit from treatment as documented by the MAS-PM immediate or delayed recall score, both of which showed a significant treatment effect. Performance on measures of cognitive dysfunction aside from learning and memory impact the benefit from KF-mSMT® treatment. Implications for cognitive rehabilitation for individuals with TBI are discussed. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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