Fluorinated a-aminophosphonates-a new type of irreversible inhibitors of serine hydrolases.

Autor: Makhaeva, G. F., Malygin, V. V., Aksinenko, A. Yu., Sokolov, V. B., Strakhova, N. N., Rasdolsky, A. N., Richardson, R. J., Martynov, I. V.
Předmět:
Zdroj: Doklady Biochemistry & Biophysics; Jan/Feb2005, Vol. 400 Issue 1-6, p92-95, 4p, 2 Charts, 1 Graph
Abstrakt: Presents the results of a clinical study on the interaction of fluorinated α-aminophosphonates (FAP) with several serine hydrolases. Role of serine hydrolases in determining the toxic action of organophosphorus compounds; Examination of the molecular properties of FAP; Melting points of FAP 3.
Databáze: Complementary Index