| Autor: |
Koroğlu, Mehmet, Ayvaz, Muhammed Ali, Tunç, Nurettin, Bulut, Nuriye Esen, Ulaşoğlu, Celal, Tuncer, İlyas, Akyüz, Ümit |
| Předmět: |
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| Zdroj: |
Journal of Enterocolitis; Dec2022, Vol. 1 Issue 3, p61-67, 7p |
| Abstrakt: |
Objective: Bone mineral density is usually decreased in inflammatory bowel diseases. Patients with inflammatory bowel diseases seem to have a multifactorial pathogenesis of their osteoporosis. The aim of our study is to determine the risk factors affecting bone mineral density in inflammatory bowel diseases. The aim of our study is to determine the risk factors affecting bone mineral density in inflammatory bowel diseases. Methods: This is a cross-sectional, multicenter study involving 121 ulcerative colitis, 129 Crohn's disease patients, and 65 healthy controls. Results: The difference between Crohn's disease and healthy controls in terms of osteopenia, osteoporosis, low bone mineral density, and T- and Z-scores were strongly significant (P < .01). Also the difference between T- and Z-scores in terms of osteopenia and low bone mineral density was strongly significant between ulcerative colitis and healthy controls (P < .01), in terms of osteoporosis, it was significant between ulcerative colitis and healthy controls (P < .05). In logistic forward stepwise analysis, disease activity and >5 g cumulative corticosteroid dose use were determined as risk factors for osteopenia, osteoporosis, and low bone mineral density in Crohn's disease. Disease activity and use of >5 g corticosteroid for osteopenia, body mass index and >5 g corticosteroid use for osteoporosis, and >5 g corticosteroid use for low bone mineral density were determined as risk factors in ulcerative colitis. Conclusion: Bone mineral density in inflammatory bowel diseases is significantly lower than that in healthy individuals. Low bone mineral density is mostly found in Crohn's disease. Factors affecting bone mineral density are multifactorial in inflammatory bowel diseases, and it is widely accepted that bone mineral density is reduced. It is important to perform dual-energy x-ray absorptiometry regularly for patients with risk factors. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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