Association of serum vitamin D levels with coronary artery angiographic findings; A cross-sectional study.
| Autor: | Aslanabadi, Naser, Jangioskouei, Nader, Jafari, Negar, Pakmehr, Azin, Khalaji, Amirreza, Esmailnejad, Azam, Moslemi, Mohammadreza, Khabbazi, Shahin |
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| Předmět: |
RESEARCH
ACADEMIC medical centers CROSS-sectional method RESEARCH methodology CARDIOVASCULAR diseases VITAMIN D CORONARY angiography SEVERITY of illness index RISK assessment T-test (Statistics) CORONARY artery disease CHI-squared test VITAMIN D deficiency STATISTICAL correlation DATA analysis software LOGISTIC regression analysis DISEASE risk factors EVALUATION DISEASE complications |
| Zdroj: | Journal of Preventive Epidemiology; Mar2023, Vol. 8 Issue 1, p1-4, 4p |
| Abstrakt: | Introduction: Coronary artery diseases (CADs) are a global health issue. In addition, several researchers have reported a correlation between serum vitamin D levels and different aspects of cardiovascular diseases. It has been reported that vitamin D can modulate atherothrombosis. Objectives: This study aimed to investigate the correlation between 25-hydroxyvitamin D and CAD severity. Patients and Methods: This is a cross-sectional study. The study sample consisted of patients undergoing elective coronary angiography. To assess 25-hydroxyvitamin D levels, fasting samples were collected from patients. Patients were included in this study based on the number of involved coronary vessels and SYNTAX classification. Results: The serum levels of 25-hydroxyvitamin D were significantly lower in the group of patients with CAD and cardiovascular disease than in the control group (P < 0.001). This study showed, severe vitamin D deficiency caused significantly higher SYNTAX scores (P < 0.001). Conclusion: The results of our study showed, vitamin D deficiency might have an essential relationship with the severity and incidence of CAD; however, we recommend further studies to investigate the preventing effects of vitamin D supplementation, primarily through intervention studies. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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