COVID-19-ASSOCIATED ACUTE PANCREATITIS: A SYSTEMATIC REVIEW OF CASE REPORTS.

Autor: Rahimian, Zahra, Feili, Afrooz, Ghaderpanah, Rezvan, Sadrian, Seyedhassan, Hosseini, Seyed Ali, Ranjbar, Maryam, Feili, Maryam, Lankarani, Kamran Bagheri
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Zdroj: Epidemiological Review / Przegląd Epidemiologiczny; 2023, Vol. 77 Issue 1, p66-73, 8p
Abstrakt: INTRODUCTION. Coronavirus disease 2019 (COVID-19) mainly involves the respiratory system but can also affect the digestive system and cause several gastrointestinal manifestations. Acute pancreatitis has been reported as one of the rare presentations of COVID-19. This study aimed to systematically review case reports on COVID-19-associated acute pancreatitis. METHODS. Publications were retrieved through a comprehensive search in four databases on October 1, 2021. Eligible ones that demonstrated the potential association of acute pancreatitis and COVID-19 were included for data extraction. RESULTS. After screening 855 citations, 82 articles containing 95 cases were included, and their data were extracted. The most common presentation was abdominal pain (88/95, 92.6%), followed by nausea/vomiting (61/95, 64.2%). Mortality was reported in 10.5% of cases. The initial presentation was acute pancreatitis, COVID-19, and concomitant in 32.6% (31/95), 48.4% (46/95), and 18.9% (18/95) of cases, respectively. Among the included cases, acute pancreatitis severity was associated with ICU admission, COVID-19 severity, and the outcome. Also, the initial presentation was associated with COVID-19 severity (P values =0.05). CONCLUSIONS. Current evidence indicates that acute pancreatitis can present before, after, or concomitant with COVID-19. Appropriate investigations should be performed in cases with suspicious clinical presentations. Longitudinal studies should address whether or not, there is a causative relationship between COVID-19 and acute pancreatitis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index