| Autor: |
Adewale, Omowumi O., Odebode, Monsurat O., Mustapha, Maryam O., Adetuyi, Oluwatosin A., Adeleke, Monsuru A. |
| Předmět: |
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| Zdroj: |
Tanzania Journal of Science; 2022, Vol. 48 Issue 3, p559-568, 10p |
| Abstrakt: |
Urinary schistosomiasis is of public health significance in sub-Saharan Africa with its prevalence being linked to carcinogenesis. However, there is a paucity of data to support this relationship. This study explored the prevalence and intensity of Schistosoma haematobium infections and its associations with cancer and hepatorenal function alterations in villages along the Asejire dam in the State of Osun, Nigeria. Urine samples from 152 consented participants (aged 18-75 years) from four communities were collected and examined for Schistosoma haematobium using the microscopy method. The blood serum of randomly selected infected and non-infected individuals (10 per group) was screened for tumor, inflammatory and hepatorenal function biomarkers. From the results, only one out of the four communities recorded cases of schistosomiasis with a prevalence of 26.5% (22/83) and overall infection prevalence was 14.47% (22/152). There was no statistical difference (p = 0.05) in kidney, liver antioxidants, and lipid peroxidation markers in the infected and non-infected participants. The concentrations of antioxidants, inflammatory, and tumor markers were higher in Schistosoma infected individuals as compared with non-infected individuals. This justifies the need to monitor schistosomiasis-infected individuals for tumor, inflammatory and hepato-renal function biomarkers before they develop into cancer, liver, and kidney failure. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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