| Autor: |
Casola, S., Sindaco, P., Lonardi, S., Zanardi, F., Neuman, H., Lorenzi, L., Balzarini, P., Morello, G., Varano, G., Bugatti, M., Chairini, M., Bertolazzi, G., Arima, H., Ranise, C., Giampaolo, S., Garzon, D., Capaccio, P., Mainoldi, F., Daffini, R., Zini, S. |
| Předmět: |
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| Zdroj: |
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p112-113, 2p |
| Abstrakt: |
B cell receptor (BCR) critically contributes to the growth of multiple types of mature B cell neoplasms, representing a preferred target of therapy. Strikingly, whereas IgH SP + sp DHL/THL GCB lymphomas retained IgM expression, IgH SP UND sp lymphomas systematically completed IgH class-switching, yet failed to assemble signaling-competent Ig/CD79B/A BCR complexes. IMMUNOGLOBULIN CLASS DICTATES TRANSFORMATION TRAJECTORY AND BCR STATUS OF MYC/BCL2 DOUBLE-HIT LYMPHOMA: BIOLOGY AND CLINICAL IMPLICATIONS. [Extracted from the article] |
| Databáze: |
Complementary Index |
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