HIGH‐DOSE METHOTREXATE PLUS RCHOP: EFFICACY AND TOXICITY IN THE PREVENTION OF CENTRAL NERVOUS SYSTEM RELAPSE IN PATIENTS WITH DIFFUSE LARGE B CELL LYMPHOMA.

Autor:	Casado, M., Martin, X., Arzuaga, J., Lobo, A., Rodriguez, E., Fernandez, A., Gil, M. A., Amutio, M. E., Garcia‐Ruiz, J. C.
Předmět:	B cell lymphoma DIFFUSE large B-cell lymphomas CENTRAL nervous system DISEASE relapse METHOTREXATE
Zdroj:	Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p724-724, 1p
Abstrakt:	B Introduction: b Prophylactic high dose methotrexate (HD-MTX) is widely used for preventing central nervous system (CNS) relapse in patients with diffuse large b cell lymphoma (DLBCL), as intravenous HD-MTX achieves excellent blood-brain barrier penetration. HIGH-DOSE METHOTREXATE PLUS RCHOP: EFFICACY AND TOXICITY IN THE PREVENTION OF CENTRAL NERVOUS SYSTEM RELAPSE IN PATIENTS WITH DIFFUSE LARGE B CELL LYMPHOMA CNS-IPI score classified 9 patients (47.3%) as high risk of CNS relapse, 5 (26.3%) as intermediate risk and 5 (26.3%) as low-risk. [Extracted from the article]
Databáze:	Complementary Index
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