Autor: |
Soong, D., Thieblemont, C., Karavitis, J., Hess, B., Caimi, P., Feldman, T., Hutchings, M., Sureda, A., Szafer‐Glusman, E., Sacchi, M., Jure‐Kunkel, M., Adya, N., Chiu, C. |
Předmět: |
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Zdroj: |
Hematological Oncology; Jun2023 Supplement S2, Vol. 41, p326-328, 3p |
Abstrakt: |
In patients who responded to epcoritamab, ctDNA levels decreased rapidly, with the majority of patients achieving CR having a deep ctDNA response by C3D1. B Results: b ctDNA quantification was concordant between the assays when within the dynamic range of the clonoSEQ assay (>80% in paired samples tested); however, a greater sensitivity of the AVENIO assay was observed, allowing further exploratory analyses of ctDNA using this platform. B Introduction: b The emergence of novel, more potent therapeutics in the treatment of patients with large B-cell lymphoma (LBCL) has resulted in higher rates of responses and highlighted a need for additional methods, such as minimal residual disease (MRD), to determine the depth and quality of response and potentially guide duration of treatment. [Extracted from the article] |
Databáze: |
Complementary Index |
Externí odkaz: |
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