Deregulated hsa‐miR‐23a‐3p and hsa‐mir‐148a‐3p influence key processes in classic Hodgkin lymphoma (cHL) pathogenesis.

Autor: Paczkowska, J., Janiszewska, J., Ustaszewski, A., Bein, J., Skalski, M., Schneider, M., Bednarek, K., Hansmann, M., Dzikiewicz‐Krawczyk, A., Rozwadowska, N., Hartmann, S., Giefing, M.
Předmět:
Zdroj: Hematological Oncology; Jun2023 Supplement S2, Vol. 41, p317-318, 2p
Abstrakt: B Introduction: b We previously performed global miRNA expression profiling of cHL vs. non-Hodgkin lymphoma (NHL) cell lines and sorted germinal centre B-cells (GCB). Whereas overexpression of miR-148a in three cHL cell lines caused a 32% decrease ( I p i < 0.05) in proliferation in the KM-H2 cell line compared to empty vector transductions. Deregulated hsa-miR-23a-3p and hsa-mir-148a-3p influence key processes in classic Hodgkin lymphoma (cHL) pathogenesis. [Extracted from the article]
Databáze: Complementary Index