The RNA helicase DDX21 cooperates with ETS1 and FLI1 in cell cycle regulation and small nucleolar RNA processing to sustain the survival of DLBCL cells.

Autor:	Sartori, G., Priebe, V., Cascione, L., Favre‐Juilland, M., Chung, E. Y., Napoli, S., Arribas, A., Rinaldi, A., Miazza, M. Thome, Bertoni, F.
Předmět:	CELL cycle regulation RNA helicase NON-coding RNA DIFFUSE large B-cell lymphomas LIQUID chromatography-mass spectrometry
Zdroj:	Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p250-251, 2p
Abstrakt:	B Introduction: b We have previously shown that the two ETS transcription factors ETS1 and FLI1, co-mapped in the 11q24.3 region, are recurrently gained in up to 25% of diffuse large B cell lymphomas (DLBCL), and largely co-regulate a series of genes involved in B cell signaling, differentiation and cell cycle (Bonetti et al., 2013; Priebe et al., 2020; Sartori et al., 2021). We focused on the novel ETS1 interactor DDX21, an RNA helicase also regulated by FLI1 (Sartori et al., 2021). [Extracted from the article]
Databáze:	Complementary Index
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