| Autor: |
Fischer, A., Moreno, N., Interlandi, M., Albert, T. K., Mormann, J., Glaser, S., Patil, P., Balbach, S., Wagener, R., Bens, S., Dahlum, S., Göbel, C., Graf, M., Kremer, E., de Faria, F. W., Melcher, V., Hartmann, W., Herbrüggen, H., Robert, S., Dugas, M. |
| Předmět: |
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| Zdroj: |
Hematological Oncology; Jun2023 Supplement 1, Vol. 41, p192-192, 1p |
| Abstrakt: |
LACK OF SMARCB1 EXPRESSION CHARACTERIZES A SUBSET OF PERIPHERAL T-CELL LYMPHOMAS ENRICHED IN CHILDREN AND YOUNG ADULTS B Methods: b SMARCB1 (INI1) gene and protein expression was assessed in 315 patients with diverse mature T cell lymphomas by array-based mRNA profiling, immunohistochemistry and/or Western Blot. Comparison of the DNA methylome of human and murine PTCL-NOS SP Smarcb1- sp showed similar DNA methylation profiles, with hypermethylation of T-cell-related genes and hypomethylation of genes involved in myeloid development. [Extracted from the article] |
| Databáze: |
Complementary Index |
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