| Autor: |
Pratiwi, Ariyati Retno, Hussein, Mohd Zobir, Istikharoh, Feni, Abidin, Zefri Zainal, Istiqamah, Irma, Marzely, Fadhillah, Jasmine, Salwa, Naibaho, Laura |
| Předmět: |
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| Zdroj: |
Systematic Reviews in Pharmacy; 2023, Vol. 14 Issue 3, p159-163, 5p |
| Abstrakt: |
Objective: Therefore, this study aimed to determine the physicochemical characterization of Demineralized Freeze Dried Dentine Matrix Nanoparticle (DFDDMNP) for enhance bone repair. Materials and Methods: Human tooth were minced into particles (Ø<1 mm), demineralized and freeze dried. Thorough physicochemical and biochemical characterizations of native and demineralized freeze dried materials were performed by Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), Brunauer-Emmett-Teller (BET), Field Emission Scanning Electron Microscopy (FESEM), and Thermogravimetric analysis/Derivative Thermogravimetry (TGA/DTG). Results: For the physicochemical characterization, DFDDM-NPs appeared non porous structure, near spherical shapes of various size, and it appeared agglomerated nanoparticle of around 10-50 nm. DFDDM-NPS is type IV Isotherm and Hysteresis H3. The pore structure showed that 18 m2/g, pore diameter is about 5-3 nm. As 86%-99% DFDDM-NPs can be remaining and stable down to 1000°C. Conclusion: DFDDM-NPs would allow the development of new bone graft. Further studies are recommended. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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