The Effect of Vaginal Bleeding in Early Pregnancy on First Trimester Screening Test, Uterine Artery Doppler Indices and Perinatal Outcomes.
| Autor: | Balikoglu, Meric, Bayraktar, Burak, Yurtkul, Azra Arici, Ozeren, Mehmet |
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| Předmět: |
UTERINE hemorrhage
PREGNANCY proteins STATISTICAL power analysis CONFIDENCE intervals ARTERIES FIRST trimester of pregnancy MISCARRIAGE MEDICAL screening MANN Whitney U Test FISHER exact test UTERUS PREGNANCY outcomes COMPARATIVE studies T-test (Statistics) DOPPLER ultrasonography DESCRIPTIVE statistics CHI-squared test SECOND trimester of pregnancy ODDS ratio DATA analysis software CHORIONIC gonadotropins FETAL ultrasonic imaging FETAL monitoring LONGITUDINAL method DISEASE complications PREGNANCY |
| Zdroj: | Medical Records; 2023, Vol. 5 Issue 2, p393-399, 7p |
| Abstrakt: | Aim: We aimed to prospectively investigate the effect of first trimester vaginal bleeding on first trimester screening test, uterine artery (UtA) Doppler results and perinatal outcomes. Material and Methods: Fifty cases that presented with vaginal bleeding in the first trimester between 2019 and 2020 constituted the early vaginal bleeding (abortus imminens-threatened abortion) group and fifty cases without a history of vaginal bleeding in pregnancy constituted the control group. Demographic datas were noted at the first visit. Both groups were followed up until birth. First trimester screening test (double screening test) between 11-14 weeks and UtA Doppler examination between 20-24 weeks of gestation was performed. Perinatal outcomes and values of nuchal translucency (NT), free ß human chorionic gonadotropin (f ß-hCG), pregnancy-associated plasma protein A (PAPP-A), and UtA Doppler were compared between the two groups. Results: There was no statistically significant difference was found between the two groups in terms of NT and PAPP-A among the first trimester screening test results (p=0.741 and p=0.937, respectively). In the group with threatened miscarriage, f ß-hCG value was numerically higher, but there was no statistically significant difference (1.24±0.59 vs. 1.1±0.93, p=0.057). In the Doppler examination of the UtA, there was no statistically significant difference between the groups in terms of systolic/diastolic ratio, pulsatility index, resistive index and the presence of a notch (p=0.713, p=0.528, p=424, p=0.538, respectively). Perinatal complication rate was statistically significantly higher in the study group (p=0.013; Odds Ratio:3.2, 95% CI 1.2-8.3). Conclusion: Contrary to some different studies, we believe that first trimester screening test parameters or uterine artery Doppler flow indices do not have a place in predicting perinatal outcomes of pregnant women with a history of vaginal bleeding in the first trimester. In addition, early vaginal bleeding does not significantly affect screening parameters. Perinatal complication rate was found to be statistically significantly higher in the group with a history of threatened miscarriage. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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