| Autor: |
Sanusi, F., B. S., Okediran, K. Y., Suleiman, G. J., Akorede |
| Předmět: |
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| Zdroj: |
Savannah Veterinary Journal; 2022, Vol. 5 Issue 1, p15-19, 5p |
| Abstrakt: |
Introduction: Turmeric rhizome powder (Curcuma longa) contains curcumin a polyphenol derived from dietary spice turmeric which possesses anti-inflammatory and anticancer properties when administered. Turmeric powder is used indiscriminately as food spices without recourse to measurement just to achieve desired result. The study was conducted to ascertain the haematological and some biochemical parameters when male Albino rats were subjected to graded doses of turmeric rhizome powder. Methods: Total of twenty male Albino rats were used for the study, they were randomly divided into four groups (A-D). Group A served as the control while groups B to D were intragastrically administered solubilized turmeric rhizome powder in distilled water at 400, 600 and 800 mg/kg body weight respectively in divided doses once daily for eight weeks. At the termination of the experiment, blood samples were obtained into EDTA bottles for haematological studies while serum samples were used for biochemical analyses. Results: There was no significant (P<0.05) change in the haematological parameters and erythrocyte indices of the exposed rats compared to the control groups. However, there was a mild significant (P<0.05) increase in the aspartate and alanine amino transferases of the exposed groups compared to the control which was attributed to minor stress due to endogenous cortisol released. Other biochemical parameters measured such as creatinine, blood urea nitrogen were not significantly (P<0.05) affected. Significance: It can be concluded that powdered rhizome turmeric (Curcuma longa) is safe at graded doses of 400, 600 and 800 mg/kg body weight when administered intragastrically in divided doses. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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