Non-Alcoholic Fatty Liver Disease (NAFLD): A review of pathophysiology with Clinical correlation Grade 1 and Grade 2 NAFLD.

Autor: Gujral, Jaspreet Kaur, Karunanand, Busi, Sarin, Monu, Gaurav, Abhishek, Kashyap, Preeti
Předmět:
Zdroj: Indian Journal of Basic & Applied Medical Research; Dec2022, Vol. 12 Issue 1, p33-38, 6p
Abstrakt: Non-alcoholic fatty liver disease (NAFLD) is one of the most chronic hepatic diseases in the world and occurs in about 25% of individuals worldwide. It is considered as the manifestation of metabolic syndrome in liver, and its development and progression is influenced by complex interaction of environmental and genetic factors. In this review we discuss the pathophysiology, risk factors, imaging in NAFLD, differential diagnoses, and the commonly used grading and staging systems of NAFLD. Diagnosis of NAFLD is defined as presence of hepatic steatosis, ballooning and lobular inflammation with or without fibrosis. Weight loss, dietary modification, and the treatment of underlying metabolic syndrome remain the mainstays of therapy once the diagnosis is recognized. Dietary recommendations and lifestyle interventions, weight loss, and the treatment of underlying metabolic syndrome remain the mainstays of therapy once the diagnosis is established with promising results but are difficult to maintain. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index