Patch Testing With Cobalt in Adults: A North American Contact Dermatitis Group Experience, 2001-2018.

Autor: Silverberg, Jonathan Ian, Patel, Nisha, Warshaw, Erin M., DeKoven, Joel G., Belsito, Donald V., Atwater, Amber R., Taylor, James S., Sasseville, Denis, Reeder, Margo J., Houle, Marie-Claude, DeLeo, Vincent A., Maibach, Howard I., Fowler Jr, Joseph F., Zug, Kathryn A., Pratt, Melanie D.
Zdroj: Dermatitis (Mary Ann Liebert, Inc.); May/Jun2023, Vol. 34 Issue 3, p209-217, 9p
Abstrakt: Background: Cobalt is a recognized cause of allergic contact dermatitis (ACD); however, detailed information on patient characteristics, sites, and sources is lacking. Objective: The aimof the study is to assess trends in patch test reactions to cobalt and associated patient characteristics, common sources, and body sites affected. Methods: The study used a retrospective analysis of adult patientswhowere patch tested to cobalt by the NorthAmerican Contact Dermatitis Group between 2001 and 2018 (n = 41,730). Results: Overall, 2986 (7.2%) and 1362 (3.3%) had allergic or currently relevant patch test reaction to cobalt, respectively. Patients with versus without an allergic patch test reaction to cobalt were more likely to be female, employed, have a history of eczema or asthma, beBlack, Hispanic, or Asian, and have occupational-related dermatitis. The most commonly identified sources of cobalt in allergic patients included jewelry, belts, and cement, concrete, and mortar. Affected body site(s) varied by cobalt source among patients with currently relevant reactions. Occupational relevance was found in 16.9% of patients with positive reactions. Conclusions: Positive patch test reactions to cobalt were common. Themost common body sites were the hands, and affected site varied by the source of cobalt. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index