| Autor: |
Zuhra, Cut Fatimah, Sinaga, M. Zulham Efendi, Suharman, S., Nasution, Riska Alvi Salsabila, Manullang, Hendrik, Ginting, Ninta Margaretha, Sebayang, Yessica Heliasni, Nurhadija, Siti |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 2023, Vol. 2626 Issue 1, p1-8, 8p |
| Abstrakt: |
Breadfruit starch can be modified into nanoparticles that function as a drug delivery matrix. The study used lintnerization method to modify the starch into nanostarch in order to increase the binding capacity to the active compound, reduce swelling ability, increase the paste stability and its uniformity in nanosize. In this research, a drug delivery matrix formulation has been designed. The resulting starch microemulsion preparation was tested for organoleptic, microemulsion particle size, microemulsion type stability and an in vitro test. Microemulsion preparations were produced with the tween 80 formula, then mefenamic acid was dissolved in 0.1 N NaOH, propylene glycol, virgin coconut oil (VCO) and starch solution. The particle size of the resulting microemulsion was 51.62 nm, 109.14 nm, 98.23 nm, the preparation was stable after a cycling test, and the physical character was microemulsion type o/w with a pH value ranging from 9.4-10. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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