Antioxidant and anti-aging activities of cabbage ethanolic extract in gel formulations.

Autor: Tarigan, Lela Diyana Br., Lister, I. Nyoman Ehrich, Fachrial, Edy, Amansyah, Adek
Předmět:
Zdroj: AIP Conference Proceedings; 2023, Vol. 2626 Issue 1, p1-6, 6p
Abstrakt: Photoaging is an aging process that causes the reduction of collagen and elastin fibers in the skin due to exposure to UV rays, which causes premature aging. Cabbage contains vitamin A, vitamin B1, and vitamin C. Vitamin C, flavonoid, and glutamine may act as antioxidants to neutralize free radicals and to improve the regeneration of damaged skin cells. This study aimed to evaluate the antioxidant potential of cabbage ethanolic extract using DPPH method, total flavonoids, total phenol and the anti-aging activity of gel formulations with a concentration of 2%; 4%; 6%. Skin analysis was observed such as moisture content, oil content, texture, collagen, wrinkles, pigment, sensitivity, and pores. The antioxidant activity of cabbage EtOH extract showed IC50 of 176.558 µg/mL, total phenolic content of 45.090 mg GAE/g extract and total flavonoids of 1.6834 mg QE/g extract. The best anti-aging activity was obtained in the F3 formulation compared to the F1 and F2 formulation. The percentage of water content recovery was 40.68%; oil content of 37.24%; texture by 80%; collagen 19.05%; wrinkles of 70.93%; 50.88% stains; sensitivity of 47.51%; pores of 44.18%. The ethanolic extract of cabbage displayed potential antioxidant and anti-aging activity. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index