FDG and Non-FDG Radiopharmaceuticals for PET Imaging in Invasive Lobular Breast Carcinoma.

Autor: Gilardi, Laura, Airò Farulla, Lighea Simona, Curigliano, Giuseppe, Corso, Giovanni, Leonardi, Maria Cristina, Ceci, Francesco
Předmět:
Zdroj: Biomedicines; May2023, Vol. 11 Issue 5, p1350, 14p
Abstrakt: Invasive lobular cancer (ILC) is the second most frequent histological type of breast cancer (BC) and includes a heterogeneous spectrum of diseases with unique characteristics, especially the infiltrative growth pattern and metastatic spread. [18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) is extensively used in oncology and BC patient evaluation. Its role in ILCs is considered suboptimal due to its low FDG avidity. Therefore, ILCs could benefit from molecular imaging with non-FDG tracers that target other specific pathways, contributing to precision medicine. This narrative review aims to summarize the current literature on the use of FDG-PET/CT in ILC and to discuss future opportunities given by the development of innovative non-FDG radiotracers. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index