Chemo-enzymatic synthesis of (S,S)-2,2′-(ethylenediamino)dibutan-1-ol.

Autor: Yufryakov, V. S., Tsvetikova, M. A., Bystrova, N. A., Kochetkov, K. A.
Předmět:
Zdroj: Russian Chemical Bulletin; May2023, Vol. 72 Issue 5, p1268-1273, 6p
Abstrakt: A chemo-enzymatic method is proposed for the preparation of (S,S)-2,2′-(ethylenediamino)dibutan-1-ol based on the synthesis of racemic (±)-N-carbobenzoxy-2-amino-butan-1-ol and its enantioselective acylation in the presence of lipase at a key resolution step to release the optically active alcohol. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index