Relationship between Helicobacter pylori and undifferentiated non-granulomatous anterior uveitis.
| Autor: | Pérez-Cano, Héctor Javier, Ceja-Martínez, Jimena, Tellezgiron-Lara, Vanessa, Voorduin-Ramos, Stephanie, Morales-López, Oscar, Somilleda-Ventura, Selma Alin |
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| Předmět: |
IMMUNOGLOBULINS
SCIENTIFIC observation CONFIDENCE intervals RESEARCH methodology CROSS-sectional method CASE-control method MANN Whitney U Test COMPARATIVE studies IMMUNOASSAY CHI-squared test DESCRIPTIVE statistics IRIDOCYCLITIS DATA analysis software ODDS ratio CHROMATOGRAPHIC analysis HELICOBACTER diseases LONGITUDINAL method VENOUS puncture |
| Zdroj: | Infection; Jun2023, Vol. 51 Issue 3, p765-768, 4p, 2 Charts, 1 Graph |
| Abstrakt: | Purpose: The relationship of Helicobacter pylori infection with ocular diseases, including anterior uveitis, has been reported. The objective of this study was to determine the presence of anti-H. pylori IgG antibodies in patients with idiopathic non-granulomatous anterior uveitis and compare the results with a control group. Methods: A prospective, comparative, and cross-sectional study was conducted. Patients with idiopathic granulomatous anterior uveitis and a group of control subjects were included. The presence of anti-H. pylori IgG antibodies was determined. The chi-square test was performed for comparative analysis with GraphPad Prism V5.0 software. Results: Thirty patients with idiopathic non-granulomatous anterior uveitis and 35 control subjects were included. In the determination of anti-H. pylori IgG antibodies, 24 (80%) patients and 19 (54%) control subjects were positive. A significant difference (p = 0.0263) was found between the groups and an odds ratio (OR) of 3.37. Conclusions: A direct relationship was found between the presence of anti-H. pylori IgG antibodies and idiopathic non-granulomatous anterior uveitis. An association can be established between idiopathic non-granulomatous anterior uveitis and H. pylori infection, without this being a causal or physiopathogenic relationship. [ABSTRACT FROM AUTHOR] |
| Databáze: | Complementary Index |
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