Creutzfeldt–Jakob disease in a post-COVID-19 patient: did SARS-CoV-2 accelerate the neurodegeneration?

Autor:	Alloush, Taha K., Alloush, Adel T., Abdelazeem, Yaser, Shokri, Hossam M., Abdulghani, Khaled O., Elzoghby, Ahmed
Předmět:	CREUTZFELDT-Jakob disease SARS-CoV-2 COVID-19 pandemic
Zdroj:	Egyptian Journal of Neurology, Psychiatry & Neurosurgery; 5/22/2023, Vol. 59 Issue 1, p1-7, 7p
Abstrakt:	Background: Creutzfeldt–Jakob disease (CJD) is a rare, fatal neurodegenerative disorder, with few months as a usual duration from onset to death. Case presentation: In this case report, a patient of Sporadic CJD (sCJD) who presented one month after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The diagnosis of this case was established after confirming findings from clinical, neurophysiology, radiological, and laboratory features of this disease. Conclusion: Putting in mind all the updated data on the pathogenesis of CJD and the immune responses to SARS-CoV-2, we can suggest that COVID-19 can lead to accelerated pathogenesis and exaggerated manifestations of this fatal neurodegenerative disease. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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