| Autor: |
Ramasamy Devaraj, Prashanthi Krishna Dharma, Arasi, Selva, Shalini, Sai, Vasudevan, Anand Kumar |
| Předmět: |
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| Zdroj: |
Medico-Legal Update; Jan-Mar2023, Vol. 23 Issue 1, p36-41, 6p |
| Abstrakt: |
Background: Autopsy changes in sudden cardiac death due to Acute Myocardial Infarction (MI), is a real challenge for Forensic Pathologist. Immuno-histochemistry has proved significant role in identifying myocardial necrosis. Aim: To find the incidence of deaths due to myocardial ischemia, its changes among the postmortem cases and the role of C9 in identifying deaths due to myocardial infarction by immuno-histochemical staining methods among autopsy cases. Materials and Methods: Study was conducted on 44 autopsy cases. Multiple tissue samples were collected from the heart and other organs, tissue processing and paraffin blocks were made and Hemotoxylin and Eosin (H&E) staining and immuno-histochemical expression was performed for C 9 marker to find out the myocardial necrosis. Data were analyzed using Statistical Package for Social Sciences (SPSS-20) as descriptive statistics. Result: Common age group was 51-60 years. 75% of them were found to have co morbid conditions. Histopathology for C9 showed 66% to be positive. Conclusion: Complement C9 factor was used as a reliable marker for identification of early MI in cases which do not show significant histopathological changes with haemotoxylin and Eosin stains. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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