Docking and PASS-Assisted Evaluation of Furaldehyde Substituted Benzimidazoles as Anthelmintic Agents.

Autor:	Pattanayak, P., Mishra, G. P.
Předmět:	FURFURAL STANDARD deviations BENZIMIDAZOLES HELMINTHIASIS ELEMENTAL analysis SCHIFF bases
Zdroj:	Russian Journal of Bioorganic Chemistry; Apr2023, Vol. 49 Issue 2, p403-411, 9p
Abstrakt:	An attempt has been made to design, synthesize and evaluate novel compounds (Ia–Ih) and (IIa–IIh) against Helminthiasis. The designed compounds were synthesized and characterized by physicochemical and spectrophotometric (FTIR, Mass, 1H NMR, and elemental analysis) data. Among the compounds, compounds (Ic) and (Ig) have exhibited excellent anthelmintic activity with a good docking score and acceptable root-mean-square deviation (RMSD). [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu Full text from SpringerLink