| Autor: |
Babu, Donka Suresh, Srinivasulu, Doddaga, Yesu, Valaparla Bala, Narayana, V. V. P. C., Vatturu, Murali, Kethineni, Sajitha, Balaji, Meriga |
| Předmět: |
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| Zdroj: |
Rasayan Journal of Chemistry; Jan-Mar2023, Vol. 16 Issue 1, p527-535, 9p |
| Abstrakt: |
In pursuit of a biodynamically potent molecule, we have attempted to synthesize derivatives of piperazine by incorporating them into the Rosuvastatin intermediate. The reason behind this is that heterocyclic compounds with nitrogen atoms in their ring structure, such as pyrimidine, have great potential as drug design scaffolds. By doping piperazine into the Rosuvastatin intermediate, a series of new derivatives made up of aryl-amides, acetamides, and sulfonamides were produced. These derivatives were then assessed for their antimicrobial activity, with a few showing promising results. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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