Fabrication of Textile-Based Scaffolds Using Electrospun Nanofibers for Biomedical Applications.

Autor: Ashok, K., Babu, M., Kavitha, G., Jeyanthi, R., Ladchumananandasivam, R., da Silva, O., Manikandan, E.
Předmět:
Zdroj: Advances in Polymer Science; 2023, Vol. 291, p136-166, 31p
Abstrakt: Even with its simplicity, ease of use, and wide variety of applications, the ELS technique has gained in popularity. The characteristics of EFs fibres (FBs) can be affected by changing process variables or polymeric solution (PLs) conditions. Many of the elements that impact ELS, however, are linked. An ideal ELS method keeps these parameters constant and consistently creates NFs with consistent physicochemical properties. The PLs might be aqueous, polymeric melt, or emulsion, resulting in NF production in various forms. Inverting the polarity and altering the collector design can also change the NF characteristics. Blending, surface functionalization, and emulsion generation are all methods for incorporating the active moiety into polymeric FBs. The multilayer polymer covering permits the incorporated active moiety to be released constantly, and the NFs may be modified to carry a variety of medications. Polymer (PLY)-derived EFs and NFs are utilized for DD, ANC, WH, BS, SiRNA delivery, stem cell treatment, and growth factors. This review compiles papers concerning the utilization of EFs and NFs in biomedical applications (BMA). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index