| Autor: |
Sun, Wei, Yuan, Yating, Shen, Xuehua, Zhang, Yiwei, Dong, Nianguo, Wang, Guohua, Li, Yuman, Liang, Bo, Lv, Qing, Zhang, Li, Xie, Mingxing |
| Předmět: |
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| Zdroj: |
European Radiology; Jun2023, Vol. 33 Issue 6, p3878-3888, 11p, 3 Charts, 3 Graphs |
| Abstrakt: |
Objectives: The prognostic value of cardiac magnetic resonance feature tracking (CMR-FT)–derived right ventricular longitudinal strain (RVLS) post-heart transplantation has not been studied. This study aimed to evaluate the prognostic significance of CMR-FT-derived RVLS, in patients post- heart transplantation and to directly compare its value with that of conventional RV ejection fraction (RVEF). Methods: In a cohort of consecutive heart transplantation recipients who underwent CMR for surveillance, RVLS from the free wall was measured by CMR-FT. The composite endpoint was all-cause death or major adverse cardiac events. The Cox regression model was used to examine the independent association between RVLS and the endpoint. Results: A total of 96 heart transplantation recipients were retrospectively included. Over a median follow-up of 41 months, 20 recipients reached the composite endpoint. The multivariate Cox analysis showed that the model with RVLS (hazard ratio [HR]:1.334; 95% confidence interval [CI]:1.148 to 1.549; p < 0.001; Akaike information criterion [AIC] = 140, C-index = 0.831) was better in predicting adverse events than the model with RVEF (HR:0.928; 95% CI: 0.868 to 0.993; p = 0.030; AIC = 149, C-index = 0.751). Furthermore, receiver operating characteristic curves revealed that the accuracy for predicting adverse events was greater for RVLS than RVEF (area under the curve: 0.85 vs 0.76, p = 0.03). Conclusions: CMR-FT-derived RVLS is an independent predictor of adverse events in post-heart transplantation, and its predictive value was better than RVEF. Therefore, our study highlighted the importance of evaluating RVLS for risk stratification after heart transplantation. Key Points: • CMR-RVLS is an independent predictor of adverse events post-heart transplantation and provides greater predictive value. • CMR-RVLS may help clinicians to risk stratification in heart transplantation recipients. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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