Structures of Nanodiamonds with Photoactive Modifiers.

Autor: Lebedev, V. T., Kulvelis, Yu. V., Soroka, M. A., Kyzyma, O. A., Vul, A. Ya.
Zdroj: Journal of Surface Investigation: X-Ray, Synchrotron & Neutron Techniques; Feb2023, Vol. 17 Issue 1, p7-16, 10p
Abstrakt: Binary and ternary complexes of europium fullerenes and diphthalocyanines with detonation nanodiamonds are obtained for the first time, which can serve as platforms for the delivery of these hydrophobic molecules into aqueous biological media for magnetic resonance imaging, photodynamic therapy, and diagnostics using luminescent labels. Detonation nanodiamonds (~4–5 nm in size) have a positive potential (30–70 mV) in an aqueous medium due to the groups (CH, COH) grafted to the surface by heat treatment in an atmosphere of hydrogen. When positively charged diamonds interact with electronegative hydrated fullerenes in an aqueous medium, the initial aggregates of each of the components are destroyed, and the electrostatic attraction between them leads to the formation of stable compact complexes ~20 nm in size, according to dynamic light scattering and neutron scattering in colloids (20°C). Binary complexes include, on average, two fullerene molecules per 30–40 diamond particles. Introducing diphthalocyanine molecules into a binary colloid yields stable ternary structures. The resulting complexes of diamonds, fullerenes, and diphthalocyanine molecules are promising for biomedical applications due to the luminescent and magnetic properties of the components. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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