Endothelial progenitor cell response to a multicomponent exercise training program in adults with cardiovascular risk factors.

Autor: Cavalcante, Suiane, Teixeira, Manuel, Gouveia, Marisol, Duarte, Ana, Ferreira, Miriam, Simões, Maria I., Conceição, Maria, Costa, Mariana, Ribeiro, Ilda P., Gonçalves, Ana Cristina, Oliveira, José, Ribeiro, Fernando
Zdroj: German Journal of Exercise & Sport Research; Jun2023, Vol. 53 Issue 2, p225-231, 7p
Abstrakt: Aim: To evaluate the effects of a multicomponent exercise program in the circulating levels of endothelial progenitor cells (EPCs) and endothelial damage among adults with cardiovascular risk factors. Materials and methods: Eleven adults with cardiovascular risk factors underwent an 18-week light-to-moderate intensity multicomponent exercise training program. Participants performed two 45 min supervised sessions per week. Blood samples were collected before and after the exercise program, and the levels of EPCs and circulating endothelial cells (CECs) were quantified by flow cytometry. Results: The circulating levels of EPCs increased by 5.0 ± 3.3% (5.0 × 10−3 ± 1.6 × 10−3% to 10.0 × 10−3 ± 2.5 × 10−3%, P < 0.001) after the exercise training, whereas no change was observed in CEC count (4.9 × 10−3 ± 2.6 × 10−3% to 6.2 × 10−3 ± 1.5 × 10−3%, P = 0.23). Conclusions: A multicomponent exercise training program improves endothelial integrity, as reflected by the increased levels of EPCs without changes in endothelial damage. These findings provide evidence to support the use of multicomponent exercise to modulate vascular competence and improve endothelial health among adults with cardiovascular risk factors. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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