Amyopathic dermatomyositis with TIF1 γ positivity treated with intravenous immunoglobulin.

Autor: Jiang, Simon W., Kwock, Jeffery T., Marano, Anne L.
Předmět:
Zdroj: Dermatology Online Journal; Mar/Apr2023, Vol. 29 Issue 2, p1-4, 4p
Abstrakt: Dermatomyositis is an inflammatory myopathy involving the skin that typically affects patients between 40-60 years of age and is more likely to be diagnosed in women. Around 10-20% of dermatomyositis cases present with subclinical or absent muscle involvement, termed "clinically amyopathic." Presence of anti-transcription intermediary factor 1y (TIFly) antibodies is an important indicator of underlying malignancy. We present a patient with anti-TIFlY-positive amyopathic dermatomyositis associated with bilateral breast cancer. The patient was safely treated with trastuzumab for breast cancer and intravenous immunoglobulin for dermatomyositis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index