Paraneoplastic or treatment-associated dermatomyositis: a diagnostic challenge.

Autor: Esperança-Martins, Miguel, Dâmaso, Sara, Carreira, Nuno, Pena, Bárbara, Correia, Catarina, Aguado-Lobo, Marta, Espinosa-Lara, Pablo, Soares-de-Almeida, Luís, Abreu Ribeiro, Leonor, Costa, Luís
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Zdroj: Dermatology Online Journal; Mar/Apr2023, Vol. 29 Issue 2, p1-5, 5p
Abstrakt: Dermatomyositis (DM) is a systemic autoimmune disorder characterized by proximal myopathy and dermatological findings. Approximately 15-30% of DM cases emerge as a paraneoplastic syndrome caused by a concomitant malignancy. Although more rare, in cancer patients DM has also been reported as a possible result of toxicity of some antineoplastic agents, such as taxanes and monoclonal antibodies. Herein, we report a 35-yearold woman with metastatic breast cancer who presented with skin lesions after initiation of paclitaxel and anti-HER2 agents. Clinical, laboratory, and histological findings were consistent with the diagnosis of DM. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index