| Autor: |
Sholikhah, Maratus, Purwanto, Ungsari Rizki Eka, Ikasari, Endang Diyah, Puspitaningrum, Ika |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 2023, Vol. 2706 Issue 1, p1-7, 7p |
| Abstrakt: |
Cassumunar Ginger essential oil is widely used as postnatal antiobesity with the main compound terpinene-4-ol. Previous studies have shown that Nanoemulsion Gel containing Cassumunar Ginger essential oil has good physical characteristics and has the potential to be developed into a antiobesity topical preparation. The purpose of this study was to determine the antiobesity pharmacological activity in vivo nanoemulsion of Cassumunar ginger essential oil gel of Swiss strain mice that had been induced by a high-fat diet. Cassumunar Ginger essential oil (CV.M&H Farm&Marine, Indonesia) and its nanoemulsion gel was prepared. A total of 20 mice were divided into four groups, namely one control group and three treatment groups. Parameters measured were body weight, food index, and feces index. Oneway anova test showed there were significant differences in weight loss between treatment groups compare to the control group. Nanoemulsion Gel containing Cassumunar Ginger essential oil 2% had better antiobesity activity compared with other test groups. But, there were not significant differences in antiobesity activity between Essential Oil and Nanoemulsion Group. Cassumunar Ginger essential oil nanoemulsion gel has the potential to be developed into a topical anti-obesity preparation. Further studies are needed to obtain a more precise formula so that it can increase its anti-obesity effectiveness. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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