| Autor: |
Alsarayreh, Ahmad Z, Khleifat, Khaled M, Al-Dalain, Sa'ed M, Al-Saraireh, Yousef M, Qaisi, Yaseen T Al, Alfarrayeh, Ibrahim I, AL-Qaraleh, Samer Y |
| Předmět: |
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| Zdroj: |
Journal of Burn Care & Research; May/Jun2023, Vol. 44 Issue 3, p563-572, 10p |
| Abstrakt: |
This study aimed to see how effective Globularia arabica and Malva slyvestries -based cream formulations were at healing scald burn wounds in rats. Depending on ointment, preparations of 1%, 5%, and 10% w/w were created. For comparison, an ointment base and a regular burn cream composed soframycine were utilized. Rats introduced a burn by solidifying equipment at 100°C on a 14-mm2 shaved dorsal region. A deep second-degree burn was created, and the percentage of wound contraction was measured over the next 15 days. The rats were euthanized on days 8 and 15, and histological slides were prepared using hematoxylin and eosin staining. Compared to the control group, there was a substantial increase in wound contraction and a significant decrease in the duration of epithelialization in the based ointment-treated groups. However, as paralleled to Globularia arabica , significant (P <.05) results were observed with 10% Globularia arabica cream, whereas Malva slyverstries indicate minimal healing. Soframycine causes a substantial increase in wound contraction (P <.05). Soframycine cream with 10% Globularia arabica therapy resulted in practically complete re-epithelialization and re-structuring of wound tissue on histological examination, whereas Malva slyversries treatment resulted in low epithelization during treatment days. The findings suggest that Globularia arabica -based cream has the wound-healing capability. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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