Arterial Infusion of Combination Therapy Using Dibutyryl Adenosine 3',5'-Monophosphate and Mitomycin C for Hepatocellular Carcinoma Occluding Main Portal Vein: Case Studies.

Autor: Ishii, Kohdoh, Karube, Hitomi, Shibata, Hisao, Okabe, Haruya, Okudaira, Masahiko, Tsuchiya, Masaharu
Předmět:
Zdroj: Angiology; Dec1989, Vol. 40 Issue 12, p1072-1078, 7p
Abstrakt: Intraarterial infusion therapy combining dibutyryl adenosine 3',5'- monophosphate and mitomycin C was administered to 8 patients with hepato- cellular carcinoma occluding the main portal vein. Three patients survived more than nine months, including 1 who has been well for forty-eight months with technical imaging showing complete regression. A decreased level of serum α-fetoprotein of more than 90% was obtained in 38% of patients. Causes of death included hepatic failure, rupture of esophageal varices, acute gastric ulcer, and cerebral hemorrhage. It is concluded that the combination therapy may be useful for HCC. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index