Somatostatin and Peripheral Blood Flow in Man.

Autor: Savi, Luigi, Cardillo, Carmine, Bombardieri, Giuseppe
Předmět:
Zdroj: Angiology; Aug1985, Vol. 36 Issue 8, p511-515, 5p
Abstrakt: Somatostatin (SS), a physiological substance which inhibits secretion of GH, TSH, glucagon and insulin, was evaluated as a vasoactive agent. In normal and arteriopatic subjects SS was administered intravenously by bolus for 3 minutes and by infusion for 30 minutes. Rheography and plethysmography of lower limbs were performed before, during and after somatostatin administration. A marked improvement of blood flow, provoked by somatostatin, was observed. A reduction of heart rate was also observed. Some hypotheses about the mechanism with which SS acts upon peripheral circulation are discussed. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index