| Autor: |
A. Z., Alanazi, Alhazzani, Khalid, Alaseem, Ali M., Alanzi, Abdullah R., Al Awadh, Saeed Abdullah, Alenazi, Fahaad S., Obaidullah, Ahmad J., El-Wekil, Mohamed M. |
| Předmět: |
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| Zdroj: |
Analyst; 5/7/2023, Vol. 148 Issue 9, p2170-2179, 10p |
| Abstrakt: |
Herein, a molecularly imprinted polymer (MIP) was fabricated for specific sensing of an aminoglycoside e.g. kanamycin (KANA). Carbon paste modified with a MIP specific to Cu2+–KANA was first introduced. Copper (Cu2+) as a metal ion was used as a signal tracer and an amplifier, producing a current response measured by differential pulse voltammetry (DPV). Introducing the aminoglycoside drug into the solution containing Cu2+ did not affect the current response of the NIP/CPE. Under the optimum conditions, the as-fabricated sensor exhibited an increase in the current response in the range of 0.55–550 nM with a good limit of detection (LOD, S/N = 3) of 161 pM. The sensor exhibited many advantages including high sensitivity and selectivity, good stability and reproducibility, and cost-effectiveness. Moreover, it was successfully applied for the determination of KANA in milk and honey samples with RSD % not more than 3.3%, suggesting the reliability of the as-designed sensor. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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