Study Findings on Membranous Nephropathy Are Outlined in Reports from University Medical Center Hamburg-Eppendorf (Non-functional ubiquitin C-terminal hydrolase L1 drives podocyte injury through impairing proteasomes in autoimmune...).

Předmět:	PROTEASOMES UBIQUITIN ACADEMIC medical centers KIDNEY diseases DEUBIQUITINATING enzymes
Zdroj:	Health & Medicine Week; 5/5/2023, p5840-5840, 1p
Abstrakt:	Keywords: Autoimmunity; Enzymes and Coenzymes; Health and Medicine; Hydrolases; Immunology; Kidney Diseases and Conditions; Membranous Nephropathy; Peptides and Proteins; Proteins; Ubiquitin C; Ubiquitins EN Autoimmunity Enzymes and Coenzymes Health and Medicine Hydrolases Immunology Kidney Diseases and Conditions Membranous Nephropathy Peptides and Proteins Proteins Ubiquitin C Ubiquitins 5840 5840 1 05/02/23 20230505 NES 230505 2023 MAY 5 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- New study results on membranous nephropathy have been published. Converging biochemical, structural, mouse pathomechanistic, and clinical information we report that the deubiquitinase Ubiquitin C-terminal hydrolase L1 (UCH-L1) is induced by oxidative stress in podocytes and is directly involved in proteasome substrate accumulation. [Extracted from the article]
Databáze:	Complementary Index
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