| Autor: |
Pailin Ratanawatkul, Solomon, Joshua J., Nipon Chaisuriya, Sasithorn Watcharadetwittaya, Tumsatan, Panaya, Arunnit Boonrod, Wipa Reechaipichitkul, Apichart So-Ngern, Worawat Chumpangern, Itthiphat Arunsurat, Pawornwan Mahawarakorn, Phitphiboon Deawtrakulchai, Piroon Mootsikapun, Kaitchoosakun, Songsak, Chakthip Suttinarakorn, Napat Yodpinij, Swigris, Jeffrey J. |
| Předmět: |
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| Zdroj: |
Journal of the Medical Association of Thailand; 2023 Supplement, Vol. 106, pS123-S127, 5p |
| Abstrakt: |
Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has varied clinical and radiographic manifestations. Severe initial viral infection, cytokine release, opportunistic infection and post-viral inflammation may all contribute to progressive symptoms and severe lung injury. Acute fibrinous and organizing pneumonitis (AFOP), a rare pattern of acute lung injury characterized by intra-alveolar fibrin ball, has so far been reported associated with infections, connective tissue diseases, drugs and toxins, hematologic malignancy, altered immune status and inhalation injury. Case Report: The authors report a case of 26-year-old man with severe COVID-19 pneumonia that clinical and radiographic imaging worsened after episode of cytokine storm. The diagnosis of AFOP was confirmed by transbronchial biopsy, and the patient was successfully treated with high-dose corticosteroids. Conclusion: AFOP can be found in severe COVID-19 patients especially when clinical deterioration occurs later in disease course. Clinical suspicion is needed for prompt diagnosis and treatment. High-dose corticosteroid is an effective medication. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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