State Key Laboratory of Biotherapy and Cancer Center Researchers Detail Research in Skin Cancer (Interleukin-37 promotes DMBA/TPA skin cancer through SIGIRR-mediated inhibition of glycolysis in CD103+DC cells).
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Zdroj: | Cancer Weekly; 4/25/2023, p1065-1065, 1p |
Abstrakt: | Keywords: Cancer; Cytokines; Dendritic Cells; Enzymes and Coenzymes; Health and Medicine; Intercellular Signaling Peptides and Proteins; Interleukins; Kinase; Oncology; Skin Cancer; Skin Neoplasms EN Cancer Cytokines Dendritic Cells Enzymes and Coenzymes Health and Medicine Intercellular Signaling Peptides and Proteins Interleukins Kinase Oncology Skin Cancer Skin Neoplasms 1065 1065 1 04/24/23 20230425 NES 230425 2023 APR 25 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- A new study on skin cancer is now available. Here, we report that IL-37b-transgenic mice (IL-37tg) treated with the carcinogenic 7,12-dimethylbenzoanthracene (DMBA)/12-o-tetradecylphorbol-13-acetate (TPA) exhibited enhanced skin cancer and increased tumor burden in the skin by inhibiting the function of CD103+ dendritic cells (DCs). [Extracted from the article] |
Databáze: | Complementary Index |
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