The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old.

Autor: Endo, Shunji, Yamatsuji, Tomoki, Fujiwara, Yoshinori, Higashida, Masaharu, Kubota, Hisako, Tanaka, Hironori, Ito, Yoshitomo, Okada, Toshimasa, Yoshiatsu, Kazuhiko, Ueno, Tomio
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Zdroj: Surgery Today; May2023, Vol. 53 Issue 5, p569-577, 9p
Abstrakt: Purpose: In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoperative pneumonia may be involved in the cause. Methods: The medical records of 39 and 108 patients ≥ 80 years old who underwent total and distal gastrectomy, respectively, at 2 affiliated institutions between 2010 and 2019 were retrospectively reviewed. Prognoses were compared between the two groups, focusing on death from pneumonia. Results: The median overall survival time after total and distal gastrectomy was 21.3 and 74.1 months, respectively, with a significantly poorer prognosis after total gastrectomy than after distal gastrectomy (p < 0.01, hazard ratio [HR] 2.20, 95% confidence interval [CI] 1.37–3.53). The gastric cancer-specific survival time was significantly worse after total gastrectomy than after distal gastrectomy (p < 0.01, HR 2.73, 95% CI 1.29–5.79). The pneumonia-specific survival time was also significantly worse after total gastrectomy than after distal gastrectomy (p = 0.01, HR 3.44, 95% CI 1.25–9.48). Conclusions: Patients who underwent total gastrectomy had a poorer prognosis than those who underwent distal gastrectomy, because many patients died of pneumonia early after total gastrectomy. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index