| Autor: |
Xu, Xiangwei, Li, Lijing, Chen, Jun, Lv, Meiyan, Xi, Yiyuan, Lv, Yanxia |
| Předmět: |
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| Zdroj: |
Natural Product Research; May2023, Vol. 37 Issue 9, p1463-1469, 7p |
| Abstrakt: |
Two new prenylated flavonoid glycosides (1-2), together with five known compounds (3-7) were isolated from the EtOAc-soluble extract of the stems of Celastrus orbiculatus. The structures of new compounds were elucidated with spectroscopic and physico-chemical analyses. All isolates were evaluated for in vitro cytotoxic activities against HepG2, MCF-7, A549, and A2780 cancer cells. Among them, compound 1 showed potential antiproliferative activity on A2780 cells with IC50 value of 10.76 μM. In addition, compound 2 exhibited selective cytotoxic activity on A2780 cells with IC50 value of 26.30 μM. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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