A prospective, observational study to evaluate fetal & maternal outcome in thrombocytopenia with pregnancy at a tertiary care centre.

Autor: Dasgupta, Nabanita, Seth, Abhishek, Koley, Arnab, Patra, Kajal Kumar, Banerjee, Pradip Kumar, Chakrabarti, Prantar
Předmět:
Zdroj: Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research); 2023, Vol. 14 Issue 2, p598-611, 14p
Abstrakt: Background: Thrombocytopenia develops in 5% to 10% of women during pregnancy or in the immediate postpartum period. A low platelet count is often an incidental feature of pregnancy, but it might also provide a biomarker of a coexisting systemic or gestational disorder and a potential reason for a maternal intervention or treatment that might pose harm to the fetus. Maternal thrombocytopenia is commonly diagnosed during routine prenatal complete blood count. Aims: To determine various etiologies of thrombocytopenia in pregnancy and to study fetal outcome & maternal outcome of thrombocytopenia in pregnancy. Material and Methods: This study was a Prospective Observational Study conducted in the Department of Gynecology & Obstetrics, NRSMC&H & Department of Haematology, NRSMC&H Kolkata, West Bengal, India from April 2019 to March 2020. 100 Pregnant women with thrombocytopenia attending ANC clinic & Haematology OPD were included in the study. A suitable predesigned pretested Proforma for data collection was used. Template was generated in MS excel sheet and analysis was done on SPSS software. Result: In the present study 23(23.0%) patients were ≤20 years old, 75(75.0%) patients were 21-30 years old Pre-term delivery (69%) is significantly higher than subjects with no Pre-term delivery (20%). 31(31.0%) patients had SNCU admission, 7(7.0%) patients had neonatal thrombocytopenia, 13(13.0%) patients had IUD, 28(28.0%) patients had LBW, 11(11.0%) patients had Spontaneous miscarriage, 26(26.0%) patients had FGR. In ITP Group, 9 (25.0%) patients had preterm delivery. In PPH Group, 3(8.1%) patients were had Preclamsia. A significant higher proportion of patients had been given spinal anaesthesia (76.92%) followed by epidural anaesthesia (23.08%). Conclusion: It was found that 7 (7.0%) patients had neonatal thrombocytopenia and 50 (50%) patients had gestational thrombocytopenia. From this study, conclusion can be made that, platelet count may not be included in routine antenatal investigations. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index