| Autor: |
S., Usha Rani, C., Ashoka, R., Swetha, S, Rajesh S. |
| Předmět: |
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| Zdroj: |
Indian Journal of Public Health Research & Development; Apr-Jun2023, Vol. 14 Issue 2, p358-363, 6p |
| Abstrakt: |
Pulmonary hypertension remains leading cause of mortality despite many advances in its management. Thiamine deficiency is identified as a reversible cause of pulmonary hypertension in exclusively breastfed infants whose mothers are thiamine defecient. The present study is planned to find out the reversible pulmonary hypertension in association with thiamine deficiency. Objectives: To study the pattern of pulmonary hypertension and its associated factors due to thiamine deficiency. Methodology: It is hospital based study in a tertiary care hospital of tumkur. Pretested and pre designed questionnaire was used to collect patients socio demographic data, clinical data and the data regarding investigations and treatment and prognosis. Results: Total of 300 babies were included in the present study after taking into consideration of all inclusion and exclusion criteria. All the babies, 300 (100) belonged to Hindhu community. 234 (79.3%) belonged to class 3 socio economic status according to modified kuppuswamy classification. Majority 212 (70.6%) had only primary education and 32 (10.6%) were illiterates. 88(29.3%) had come with severe gasping. 287(95.6%) of babies had hepatomegaly and oliguria was present in 144 (48%) of babies. The majority of the infants were presented with shock 256 (85.3%), which was managed. Repeat echo was done serially and the difference in reduction of pulmonary pressure after administration of thiamine was statistically significant (p value <0.005) Conclusion: Thiamine responsive pulmonary hypertension presents as an acute condition with severe respiratory distress, vomiting in a previously well and exclusively breast fed baby. Hence clinical suspicion to recognise the symptoms early and diagnose and mere thiamine administration is life saving and which reverses the fatal condition. Health education to mothers and family members about food taboos related to use of polished rice to prevent deficiency of thiamine is also important and supplementation of thiamine as prophylaxis can also be considered in the programmes related to antenatal and postnatal care. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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