Asymmetric Total Syntheses of (–)-Dihydromaritidine and (–)-Oxomaritidine.

Autor: Yadav, Abhinay, Majumder, Satyajit, Das, Mrinal Kanti, Mondal, Ayan, Bisai, Alakesh
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Zdroj: Synlett; Apr2023, Vol. 34 Issue 7, p858-862, 5p
Abstrakt: A concise catalytic asymmetric approach to naturally occurring Amaryllidaceae alkaloids sharing a 5,10 b -ethanophenanthridine skeleton [(–)-oxomaritidine, (–)-dihydromaritidine, (–)-maritidine, and (–)- epi -maritidine] has been envisioned. The key intermediate in this strategy was obtained by a Pd(0)-catalyzed decarboxylative allylation of a 2-arylcyclohexan-1-one-derived allylenol carbonate (87%, 96% ee). [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index