Gold self-relay catalysis enabling annulative oxygenation of propargylic alcohols with O-nucleophiles.

Autor: Hao, Meng-Ying, Zhang, Yin, Lin, Na, Fu, Rong, Ji, Xiao-Shuang, Jiang, Bo, Tu, Shu-Jiang, Hao, Wen-Juan
Předmět:
Zdroj: Chemical Communications; 4/7/2023, Vol. 59 Issue 27, p4032-4035, 4p
Abstrakt: A new gold(I) self-relay catalysis reaction enabling the annulative oxygenation of propargylic alcohols with various O-nucleophiles, such as carboxylic acids, alcohols and TBHP, is reported, producing a series of functionalized benzofurans in moderate to good yields under mild conditions. This protocol benefits from the π- and σ-Lewis acid capability of gold complexes, demonstrating high molecular convergence, broad substrate flexibility, high functional group compatibility and mild conditions. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index