Clinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma.

Autor: Liberman, Paulina, Francis, Jasmine H., Mehrotra, Karnika, Tian, Jing, McGarrey, Mark P., Sobol, Ethan K., Thorne, Jennifer E., Aronow, Mary E., Berkenstock, Meghan K.
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Zdroj: Ocular Immunology & Inflammation; Apr2023, Vol. 31 Issue 3, p496-500, 5p
Abstrakt: To evaluate if there is a difference in the clinical course of primary vitreoretinal lymphoma (PVRL) in vitrectomized versus non-vitrectomized eyes. Observational multicenter retrospective case series of patients diagnosed with PVRL between 2007 and 2019, at three tertiary centers. The main outcomes were relapse rates, inflammatory parameters, and best-corrected visual acuities (BCVA). Statistical methods used were an adjusted generalized estimating equation model, and a proportional Cox model. Eighty patients (150 eyes) were followed for a median of 1.7 years. At presentation, there were no clinical differences between the groups. The relapse rate was 0.091/eye-year (EY) for vitrectomized eyes and 0.087/EY for non-vitrectomized eyes (p =.35). Vitrectomized eyes had better BCVA than non-vitrectomized eyes (p <.001). Vitrectomy had no effect on the relapse rate in eyes with PVRL. However, the decrease in vitreous cell and debris led to vitrectomized eyes having better visual acuity than non-vitrectomized eyes. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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